By Crash News Writer 
Woodford County, KY (September 14, 2025) – A devastating multi-vehicle accident involving four tractor-trailers and two passenger cars left three people dead and three others injured on Interstate 64 Saturday evening.
According to the Kentucky State Police, troopers were called to the scene near mile marker 61 on the westbound side of I-64 around 7:30 p.m. on September 13. The collision ignited a large fire, further complicating rescue and recovery efforts.
Among the deceased were two tractor-trailer drivers and one individual in a passenger car. Three additional victims sustained injuries, including one tractor-trailer operator and two occupants of a passenger vehicle. All were transported to area hospitals for treatment.
Traffic on I-64 was significantly impacted, with all lanes closed through the night. Officials confirmed that the interstate reopened by 7:15 a.m. Sunday morning.
Kentucky State Police say the cause of the collision remains under investigation, with no further details currently released.
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PLEASE TAKE NOTICE
This report is based on information released by state and local authorities and may be updated as new developments arise. For answers to commonly asked questions after a serious accident, visit our frequently asked questions in Kentucky.
- The names of the victims have not been released as officials work to notify families.
- Investigators have not yet determined whether speeding, fatigue, or mechanical failure played a role in the crash.
- Roadway closures caused by the accident were lifted as of early Sunday morning, though motorists are advised to remain cautious in the area.
If you or your family need help after this tragedy, please refer to our accident resources in Kentucky for next steps and recovery assistance.
This content is for informational use only and should not be considered legal or medical advice. It is based on reports publicly available at the time of writing. Learn more by reading our disclaimer.
If you lost a loved one in a fatal collision, contact a knowledgeable Kentucky personal injury lawyer today for support and representation.