By Crash News Writer 
Colleton County, SC (July 24, 2025) — A deadly pile-up on a storm-slicked stretch of Interstate 95 left two people dead and at least 26 others injured Wednesday afternoon during a major weather event in Colleton County.
According to reports, the crashes happened July 23 near the 40-mile marker on the southbound side of Interstate 95 during a heavy thunderstorm with nearly zero visibility. The incident involved two separate crashes and a total of 14 vehicles, including six tractor-trailers. One of the semis was carrying large sheets of plate glass that shattered, leaving glass debris up to two feet deep on the road.
The collisions occurred near the Combahee River bridge, with the second crash causing the most severe injuries. One pickup truck was wedged into the back of a semi-trailer ten feet above the roadway, while a truck driver was trapped in the crushed remains of his cab. Another victim jumped into the river to escape, later swimming to safety.
Four people were extricated from mangled vehicles using heavy rescue tools. Two victims succumbed to their injuries at the scene and were taken by the Colleton County Coroner’s Office. Nine others were transported to area hospitals, while 13 more were treated on site.
The southbound lanes of Interstate 95 were closed for 11 hours. Emergency crews from Colleton, Hampton, and Jasper Counties responded, but poor weather grounded all medical helicopters. The crash remains under investigation by South Carolina Highway Patrol and other state agencies.
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PLEASE TAKE NOTICE
The information in this article is based on initial reports from local authorities and may be subject to updates as investigations continue.
- The identities of those involved in the incident have not been released pending official confirmation and notification of next of kin.
- Further details about the accident, including toxicology results and potential charges, will be shared as they become available.
- Road closures and traffic updates related to the accident scene can be found by checking with local authorities or traffic monitoring services.
The content of this news story is for informational purposes only and should not be considered legal or medical advice. All information is based on public reports at the time of publication, and details may change as investigations progress. Readers are encouraged to seek legal counsel if they or someone they know have been involved in a similar incident. The publisher assumes no liability for actions taken or not taken based on the information provided in this article. Learn more with our disclaimer.