By Crash News Writer 
Fayette County, PA (November 12, 2025) — A devastating three-vehicle collision Monday evening in Henry Clay Township left three people dead and five others injured, prompting an extended closure of Route 40 near Laurel Road.
According to the Pennsylvania State Police, the crash occurred around 6:00 p.m. on November 10 when a tractor-trailer reportedly crossed into oncoming traffic. The rig struck a pickup truck head-on, which then collided with a van. All three vehicles sustained heavy damage and caught fire at the scene.
Authorities confirmed that the driver of the tractor-trailer, the driver of the pickup truck, and a passenger in the van were killed. Five additional people sustained injuries and were transported to nearby hospitals for medical care.
The collision caused significant delays as Route 40 remained shut down in both directions for several hours. The cause of the crash remains under active investigation.
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PLEASE TAKE NOTICE
This news article is based on preliminary reports from local and state authorities and may be revised as more facts emerge. If you have questions about fatal collisions and how to respond, visit our frequently asked questions in Pennsylvania.
- The names of the deceased have not been released pending notification of next of kin.
- Updates regarding the investigation, including potential charges or causes, will be released by officials.
- For road reopening updates, refer to local traffic reporting services and police alerts.
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This post is for informational use only and not a substitute for legal or medical advice. All details are based on public information at the time of publication. Read our full disclaimer.
If you have lost someone or were seriously injured in a crash, call a Pennsylvania personal injury lawyer immediately to protect your legal rights.