By Crash News Writer 
Los Angeles, CA (October 23, 2025) — A serious multi-vehicle collision involving a motorcycle left at least one person with major injuries Wednesday evening on Interstate 405 in Los Angeles.
According to the California Highway Patrol, the crash happened around 5:37 p.m. on October 22 in the northbound lanes of Interstate 405 near Getty Center Drive. A black motorcycle, a white Nissan Altima, a red and black Ford Mustang, and two additional vehicles were involved in the pileup.
The Los Angeles Fire Department responded to the scene and provided medical assistance. At least one person was transported to a nearby hospital with major injuries. Their current condition remains unknown.
Authorities are actively investigating the cause of the collision and reviewing all vehicles and witness accounts.
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PLEASE TAKE NOTICE
The information in this article is based on initial reports from local officials and may be updated as more details become available. For answers to common questions after a collision, please visit our frequently asked questions in California.
- The names of those involved in the crash have not yet been released.
- Investigators are working to determine how the crash occurred and whether any citations will be issued.
- Traffic delays are likely near Getty Center Drive as authorities continue their investigation and clear the scene.
If you were affected by this incident, helpful accident resources in California are available to assist you with medical and legal support.
This content is intended for informational purposes only and should not be interpreted as legal or medical advice. All details are based on publicly available reports and are subject to change. Please review our full disclaimer for more information.
After a crash involving major injuries, do not delay. Speak with a qualified California personal injury lawyer today to protect your legal rights.