By Crash News Writer 
Burbank, CA (October 20, 2025) – A deadly wrong-way crash involving multiple vehicles occurred early Sunday morning on the 5 Freeway in Burbank, killing at least one person and injuring several others.
According to the California Highway Patrol, the crash took place around 3:45 a.m. on October 19 in the northbound lanes of Interstate 5 at Alameda Avenue. Investigators said a driver heading in the wrong direction on the freeway triggered the multi-vehicle collision.
Emergency responders confirmed that at least one person died at the scene. Three other individuals sustained injuries and were transported to local hospitals for treatment. The severity of their conditions has not yet been released.
Due to the investigation and cleanup, all northbound lanes of the freeway were expected to remain closed for a minimum of two hours.
Authorities are working to determine the circumstances that led to the wrong-way crash.
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PLEASE TAKE NOTICE
This report is based on preliminary details from law enforcement and is subject to updates. For more information on what to do after a crash, visit frequently asked questions in California.
- Authorities have not yet released the identity of the person killed in the crash.
- The total number of vehicles involved has not been confirmed as the investigation continues.
- Traffic on the 5 Freeway remains impacted due to lane closures and debris removal.
If you or someone you love has been affected, you can find support and assistance through our accident resources in California.
This article is intended for general informational purposes and not legal or medical advice. Details may change as new information becomes available. See our disclaimer for more.
To discuss your legal options following a fatal crash, speak with a California personal injury lawyer today.